Treatment of CD30‐Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases
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چکیده
منابع مشابه
Expression of galectin-3 in gonads and gonadal sex cord stromal and germ cell tumors.
Galectin-3, a beta-galactoside-binding lectin, has been implicated in many human malignancies, but has seldom been studied in human gonads and gonadal tumors. The aim of our study was to investigate galectin-3 mRNA and protein expression in normal ovaries and testes as well as in a variety of 51 gonadal sex cord stromal and germ cell tumors, and two testicular seminomatous and non-seminomatous ...
متن کاملOvary: Sex cord-stromal tumors
There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterised by multiple gastrointestinal hamartomatous polyps, increased risk of various neoplasms, and melanocytic macules of the lips, buccal mucosa...
متن کاملOvarian stromal and germ cell tumors.
Cancers arising from the stromal and germ cell layers of the ovary are rare, heterogeneous, difficult to study, and require specialized multidisciplinary management. We present a clinically relevant review of the literature of these malignancies, with particular emphasis on the more typical presentations. These tumors more commonly present in younger patients and have a high cure rate. They are...
متن کاملSex cord stromal tumors-unusual presentations.
OBJECTIVES The sex cord stromal tumors (SCST) account for approximately 7% of all malignant ovarian tumors. They are endocrinologically active tumors of which granulosa cell tumors are the commonest. We describe an analysis of all cases of SCST managed, in our department over the last five years and discuss two cases of unusual presentation of these tumors. METHODS Ten cases of SCST which wer...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2017
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2017-0544